Health Condition 1: T07- Unspecified multiple injuries
Conditions
Interventions
Intervention1: Nefopam: Nefopam shall be administered in patients with multiple extremity injuries.After 48 hours of operative procedure, the patients were switched to oral medication for two weeks.
Sponsors
Ludhiana Mediways
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients (aged >= 18 years) with periarticular or multiple shaft fractures who underwent operation will be eligible for enrollment in the study.
Exclusion criteria
Exclusion criteria: The patients with pathological fracture, Pregnant females, Breast feeding females ,Substantial injury outside the skeletal system like head injury, chest or abdomen injury requiring operative intervention, liver or renal dysfunction, pelvic or spine injuries, Fracture of small bones like clavicle, hand or foot, subjects who require additional opioid or other pain relieving medication after two days in hospital stay will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of this study is to assess the satisfaction with pain relief in cases recovering from periarticular or multiple extremity fractures treated operatively who will be randomized to receive either combination of acetaminophen nefopam and tramadol (Group A)or acetaminophen and tramadol (Group B) . The primary objective of the study will be to ascertain noninferority in pain relief of drug combination of acetaminophen with nefopam to that of acetaminophen with tramadol.Timepoint: 24 hours, two weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| The aim of this study is to assess the satisfaction with pain relief in cases recovering from periarticular or multiple extremity fractures treated operatively who will be randomized to receive either combination of acetaminophen nefopam and tramadol (Group A)or acetaminophen and tramadol (Group B) . The primary objective of the study will be to ascertain noninferority in pain relief of drug combination of acetaminophen with nefopam to that of acetaminophen with tramadol.Timepoint: 24 hours, two weeks | — |
Countries
India
Contacts
Public ContactDeepak Bansal
Ludhiana Mediways
Outcome results
None listed