Health Condition 1: T149- Unspecified injury
Conditions
Interventions
None listed
Sponsors
Department of Anaesthesiology and critical care JIPMER Puducherry
Eligibility
Inclusion criteria
Inclusion criteria: All patients with trauma admitted in the ICU
Exclusion criteria
Exclusion criteria: 1. Patients who present with AKI at the time of admission in the ICU (defined by KDIGO AKI criteria ) 2. Patients with previous history of CKD( eGFR 30 or abnormal renal imaging, documented any time prior to trauma) 3. Pregnancy 4. Individuals currently on immunosuppressive therapy. 5. Patients with traumatic injury to kidney
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the diagnostic accuracy of the product of urinary TIMP-2 and IGFBP-7 in predicting the development of AKI in trauma patients admitted to the ICU.Timepoint: 0 and 24 hours post ICU admission | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To identify the relationship of renal injury markers TIMP-2 and IGFBP-7 with the need of RRT in trauma patients admitted in the ICU. 2. To identify the level of TIMP, IGF which predicts the development of AKI and its severity 3. To assess the mortality and requirement of renal replacement in these patients after 3 months of admission to ICU 4. To assess the risk factors for development of AKI in patients admitted with trauma to the critical care unit Timepoint: 0 and 24hours post ICU admission | — |
Countries
India
Contacts
Public ContactDr Magesh P
JIPMER
Outcome results
None listed