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The study of gene expressions of esophageal cancer patients in South India.

The study of global gene expression along with circulating and salivary microRNA profiling of esophageal squamous cell carcinoma in high incidence region of South India.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/09/027602
Enrollment
100
Registered
2020-09-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C15- Malignant neoplasm of esophagus Health Condition 2: C00-D49- Neoplasms

Interventions

None listed

Sponsors

Dr Naveena Kumar AN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with primary or recurrent esophageal squamous cell carcinoma of any stage. Age more than 18 years.Patients who are from southern India.

Exclusion criteria

Exclusion criteria: Patients with Esophageal adenocarcinoma. Patients who are not willing to give informed consent. Patients who are other than from Southern India

Design outcomes

Primary

MeasureTime frame
To evaluate the global gene expression profile, microRNA profile, p16 methylation in all stages of esophageal cancer.To assess the salivary microRNA profile in esophageal cancer.To study the distribution of gene expression and molecular profile with respect to environmental and dietary factors. To study the prognosis and survival outcomes in different molecular signatures. To evolve the biomarkers for the detection of esophageal cancer in high incidence region of South India.Timepoint: 3 years—

Secondary

MeasureTime frame
To retrieve the demographical, epidemiological and clinical data of esophageal cancer patients who undergo treatment in tertiary care teaching hospital. Timepoint: 3 years—

Countries

India

Contacts

Public ContactDr Mahadev Rao

Manipal College of Pharmaceutical Sciences Manipal Academy of Higher Education

mahadev.rao@manipal.edu8105706060

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026