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Effect of locally acting hormonal drug and endoscopic surgery in treatment of heavy menstrual bleeding due to adenomyosis.

Levonorgestrel intrauterine device versus combined transcervical resection of the endometrium and levonorgestrel intrauterine device in the management of Adenomyosis: A randomized clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027592
Enrollment
150
Registered
2020-09-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: combined transcervical resection of the endometrium and levonorgestrel intrauterine device: Patients with adenomyosis in this group will undergo TCRE using bipolar resectoscope (under a

Sponsors

JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with adenomyosis with HMB (Heavy menstrual bleeding) or dysmenorrhea. 2. Premenopausal women who have completed family. 3. Refractory to at least 3 months medical management (Hormonal pills).

Exclusion criteria

Exclusion criteria: 1. Chronic pelvic pain 2. Patients not willing for follow up in JIPMER 3.Acute PID 4. Coexisting fibroid/ endometriosis 5. Women desirous of future pregnancy

Design outcomes

Primary

MeasureTime frame
To compare treatment failure rates at the end of one-year follow-up in both groups.Timepoint: 3,6 and 12 months—

Secondary

MeasureTime frame
To compare menstrual flow volume, dysmenorrhea, amenorrhea rate, side effects, patient satisfaction and quality of life in both groups at the end of one-year follow-up.Timepoint: 3, 6 and 12 months.—

Countries

India

Contacts

Public ContactDr S Murali

JIPMER, Pondicherry

muralidraiims@gmail.com08940760837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026