Procedural sedation with intranasal dexmedetomidine for radiation treatment.

Procedural sedation in children for fractionated radiation treatment course:Intranasal dexmedetomidine vs oral midazolam and ketamine.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/09/027579

Enrollment

Registered

2020-09-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C729- Malignant neoplasm of central nervous system, unspecified

Interventions

Intervention1: all recruited patients will be given by intranasal and oral route: group D -intranasal dexmedetomidine and oral honey group MK - intranasal saline and oral midazolam and ketamine mixed

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1to 3

Exclusion criteria

Exclusion criteria: Children with upper respiratory tract infection, airway obstructive conditions, congenital heart disease, neurological or mental abnormality, any other systemic disease other than cancer, on hepatic enzyme inducing drugs or allergy to study drug and refusal to participate

Design outcomes

Primary

Measure	Time frame
incidence and % of successful radiationTimepoint: 10min,20min,30min,procedure, postprocedure every 10 mins till 2 hours	—

Secondary

Measure	Time frame
time to achieve sedation , time to discharge medication acceptance score, parental separation anxiety score, side effects,mean sedation score, rescue ketamine required Timepoint: 10min,20min,30min,procedure, postprocedure every 10 mins till 2 hours	—

Countries

India

Contacts

Public ContactProf Niranjan Rout

Acharya Harihar PostGraduate Institute of Cancer

rekhadas2003@yahoo.co.in9437016520

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026