FindTrial
Sign In

Per rectal diclofenac tablet (suppository) and inraveous fluid (Ringer lactate) are already proven for decreasing adverse effect (pancreatitis) after an endoscopic procedure (ERCP). We will be combining both methods to see whether they can further decrease the adverse effect of ERCP.

A prospective randomized clinical study to compare efficacy of intravenous ringer lactate or diclofenac suppository or combination of both in prevention of post endoscopic retrograde cholangio-pancreatography(ERCP) pancreatitis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027536
Enrollment
171
Registered
2020-09-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: Diclofenac rectal suppository, Ringer lactate solution, Combination of both: Patients with high risks for post ERCP pancreatitis will receive either of three interventions mentioned,po

Sponsors

Department of Gastroenterology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients having high risk factors for post ERCP pancreatitis.

Exclusion criteria

Exclusion criteria: Pregnancy, Patient with contraindication for diclofenac and ringer lactate, Patient with active acute pancreatitis, Patient not giving consent

Design outcomes

Primary

MeasureTime frame
Decrease in incidence of post ERCP pancreatitis in combination prophylaxis group,in comparison to prophylaxis by individual therapy(rectal diclofenac OR Ringers lactate)Timepoint: After 24 hours of procedure diagnosis of pancreatitis would be looked for.—

Secondary

MeasureTime frame
Decrease in hospital stayTimepoint: 24 hours after ERCP—

Countries

India

Contacts

Public ContactRavi Kacharu Thanage

Department of Gastroenterology, T.N medical college and B.Y.L Nair hospital

rathipmpp@gmail.com9322406438

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026