Health Condition 1: O149- Unspecified pre-eclampsia
Conditions
Interventions
Intervention1: Not Applicable: This is a case control observational study where blood samples will be taken for hematological parameters in cases of preeclampsia
Intervention2: NIL: NIL
Control Interv
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Patients of preeclampsia meeting following criteria Systolic blood pressure >140 and/or DBP >90 mm of Hg on two occasions at least 4 hours apart; and proteinuria of >1+ on dipstick or 300 mg/day, after 20 week of gestation
Exclusion criteria
Exclusion criteria: Chronic hypertension Overt diabetes/GDM type A2 Renal Disease Fever within previous 1 week of diagnosis Collagen vascular disorder Rheumatoid arthritis Known autoimmune disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Values of NLR,MLR,PLR,MPV,PDW in patient of preeclampsia - Correlation of these markers with severity of preeclampsia NLR: Neutrophil to lymphocyte ratio MLR: Monocyte to lymphocyte ratio PLR: Platelet to lymphocyte ratio MPV: Mean platelet volume PDW: Platelet distribution widthTimepoint: At recruitment and at 28, 32 and 36 weeks (as applicable according to the gestational age at recruitment) and at delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Maternal outcome: Eclampsia, HELLP syndrome, Mode of delivery 2.Fetal outcome: fetal growth restriction,intrauterine fetal death,prematurity and low birth weight 3.Levels of other haematological markers such as RDW, Plateletcrit, absolute values of platelet count in preeclampsia Timepoint: - Haematological markers at recruitment and at 28, 32 and 36 weeks (as applicable according to the gestational age at recruitment) and at delivery - Maternal and fetal outcomes at delivery | — |
Countries
India
Contacts
Public ContactDr Jitendra Adhikari
All India Institute of Medical Sciences New Delhi
Outcome results
None listed