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Preoperative ketamine nebulization on attenuation of incidence and severity of post-operative sore throat, hoarseness of voice and cough

Effect of Preoperative ketamine nebulization on attenuation of incidence and severity of post-operative sore throat, hoarseness of voice and cough A randomized double blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027485
Enrollment
100
Registered
2020-08-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: Nebulization: Incidence and severity of post operative sore throat hoarseness of voice and cough is assessed and duration of study is around 1 year Control Intervention1: 50 mg ketamine

Sponsors

JLN Medical College Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 20-60 years of either sex Undergoing surgeries under general anaesthesia in supine position Duration of surgery up to 2 hours ASA physical status â?? I & II

Exclusion criteria

Exclusion criteria: Age 60 years ASA physical status III & above Mallampatti grade >2 Any psychiatric disorder and history of epilepsy Neurosurgical patients with raised intracranial pressure Patients with known coronary artery disease, old myocardial infarction and ischemic heart disease Pregnancy Patient sensitive or allergic to study drug History of pre-operative sore throat, oral surgeries, asthma, chronic obstructive pulmonary disease, head and neck surgeries. Recent non-steroidal drug medication Anticipated difficult intubation Patient and/or his/her legally acceptable representative not willing to provide their voluntary written informed consent for participation in the study

Design outcomes

Primary

MeasureTime frame
To assess incidence and severity of Post-operative sore throat (POST) Post-operative Hoarseness of voice Post-operative Cough Timepoint: Duration of study is around 1 yer

Secondary

MeasureTime frame
To assess Haemodynamic changes (HR, SBP, DBP, MAP &SpO2) Side effects, if any Timepoint: Duration of study is round 1 year

Countries

India

Contacts

Public ContactDr Veena Patodi

J L N Medical college Ajmer

veenapatodi@gmail.com9414008276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026