Nasal Wash and Gargle to Mitigate COVID-19

Impact of Nasopharyngeal wash on Virion Load in COVID-19 Patients

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/08/027465

Enrollment

Registered

2020-08-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

Intervention1: Nasopharyngeal saline wash: Study group will be treated with Nasopharyngeal Saline wash along with Standard treatment for COVID 19 as follows. 1. Nasopharyngeal Wash with normal saline

Eligibility

Inclusion criteria

Inclusion criteria: Positive Patients of COVID-19

Exclusion criteria

Exclusion criteria: Inability to perform nasopharyngeal saline wash

Design outcomes

Primary

Measure	Time frame
Reduction or absence of Virion Load in RT-PCR/ in patients of COVID-19 following nasopharyngeal wash would prevent Transmissibility, Severity and Fatality. Prophylactic Nasopharyngeal Wash with normal saline and pharyngeal gargle might prevent production of Virion Load that might avert COVID19 in population at large.Timepoint: At Baseline, after 2days and after 4 days.	—

Secondary

Measure	Time frame
Decrease in FatalityTimepoint: Number of patients transferred to Intensive care;Mitigation of Severity of COVID19Timepoint: After 7days Changes in Clinical & Biochemical parameters (TLC, DLC, CRP, IL-6, )	—

Countries

India

Contacts

Public ContactUDAY SANKAR CHATTERJEE

M.R. Bangur Hospital

udaysankarchatterjee@yahoo.com9831017686

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026