Health Condition 1: I39- Endocarditis and heart valve disorders in diseases classified elsewhere
Conditions
Interventions
None listed
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: All patients above 18 years of age, with one of the above risk factors, scheduled for elective valve surgery, single, double or CABG with valve surgery on cardiopulmonary bypass will be included in the study.
Exclusion criteria
Exclusion criteria: 1. End-stage kidney disease (CKD class V) 2. Prior kidney transplantation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In patients with one risk factor for AKI, undergoing valvular heart surgery: To assess the effect of delta MAP on the incidence of post-operative AKI 24 hrs post-operatively, using the KDIGO classificationTimepoint: 24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Assess effect of CPB flow on incidence of post-operative AKI 24 hrs post-op, using KDIGO classification 2. Assess relationship between various post-op variables including mortality, use of IABP, low cardiac output state, significant inotrope use, lengths of ICU and hospital stay and incidence of AKI 3. Assess incidence of requirement of renal replacement therapy in this population 4. Correlate changes in plasma Neutrophil gelatinase-associated lipocalin (NGAL) with delta MAP on CPBTimepoint: 24 HRS | — |
Countries
India
Contacts
Public ContactDr Anity Singh Dhanyee
JIPMER
Outcome results
None listed