FindTrial
Sign In

Association of minor blood group antigen allelic polymorphism with alloimmunization in thalassemia patients.

Exploratory study for prediction of an association of clinically significant blood group antigenic allelic polymorphism with development of alloimmunization in thalassemia patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/08/027399
Enrollment
100
Registered
2020-08-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D561- Beta thalassemia

Interventions

None listed

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Written informed consent to participate in the study. 2. Confirmed cases of Thalassemia major; 3. Age range: Greater than equal to 5 years.

Exclusion criteria

Exclusion criteria: 1. Failure to obtain Written informed consent; 2. Children (Age range: Birth to

Design outcomes

Primary

MeasureTime frame
To use blood group genotyping to decipher the antigenic constitution and trace allelic polymorphism in multi-transfused patients of thalassemia.Timepoint: 12 months—

Secondary

MeasureTime frame
To identify a possible causal relationship between the identified allelic polymorphisms with development of alloimmunization or autoimmunization in such patients of thalassemia.Timepoint: 12 months—

Countries

India

Contacts

Public ContactDiptiranjan Rout

NCI-AIIMS

drdiptiranjanrout@gmail.com08727804293

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026