Health Condition 1: L910- Hypertrophic scar
Conditions
Interventions
Intervention1: Cryotherapy: Dose: A single freeze and thaw cycle of 30 seconds using open spray technique.
Route of administration: Liquid nitrogen based cryotherapy will be applied on keloids topical
Sponsors
Bankura Sammilani Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age more than 18 yrs. to 80 yrs. 2 Previously not treated keloid 3 Localised keloid 4 Informed consent obtained 5 Willing for once monthly treatment with spray cryotherapy or intralesional bleomycin injection.
Exclusion criteria
Exclusion criteria: 1 Keloid in children. 2 Pregnant and lactating women. 3 Infected or ulcerated keloid. 4 Patients suffering from peripheral vascular disease. 5 Raynaudâ??s phenomenon 6 Concomitant immune defect, heart disease, renal failure, malignancy. 7 Neurological or psychiatric disorders. 8 Participation in any clinical trial within the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess effectiveness of Cryotherapy versus Intralesional Bleomycin injection in reducing the thickness of localised keloid.Timepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the effectiveness of these two different methods in decreasing pain and itching associated with keloid.Timepoint: 6 months;To assess the improvement in quality of life with these mentioned methodsTimepoint: 6 months;To assess tolerability and safety of the mentioned methods.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Somenath Das
Bankura Sammilani Medical College and Hospital
Outcome results
None listed