Post-operative pain relief in patients undergoing laparoscopic cholecystectomy under general anaesthesia

To compare the efficacy of intraperitoneal instillation of ropivacaine and butorphanol versus ropivacaine and nalbuphine for post-operative pain relief in patients undergoing laparoscopic cholecystectomy under general anaesthesia

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/08/027342

Enrollment

Registered

2020-08-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Intraperitoneal instillation of drugs: Ropivacaine and butorphanol versus ropivacaine and nalbuphine instillation after removal of gall bladder Control Intervention1: ropivacaine and bu

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status I and II. 2. Elective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. Acute cholecystitis. 2. Carcinoma Gall bladder. 3. Hypersensitivity to study drugs. 4. Pregnant females. 5. Bleeding disorders. 6. Opioid addicts. 7. Patient refusal to participate in the study.

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of intraperitoneal instillation of ropivacaine and butorphanol versus ropivacaine and nalbuphine for post-operative pain relief in patients undergoing laparoscopic cholecystectomy under general anaesthesia.Timepoint: After extubation of patient till 24 hours.	—

Secondary

Measure	Time frame
To compare the timing of first request and frequency of rescue analgesia.Timepoint: After extubation of patient till 24 hours.	—

Countries

India

Contacts

Public ContactDr Suzen Sumeet Kaur

Sri Guru Ram Das Institute of Medical Sciences and Research

kumarianitadr1@gmail.com9815632909

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026