Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: Oral itraconazole with topical sertaconazole: Two comparable tinea lesions (size, location and symmetry) with less than or equal to one cm variation in size will be selected in each pat
Sponsors
Armed Forces Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Adults between the age of 18-65 years, clinically diagnosed as tinea corporis and tinea cruris and confirmed by positive KOH mount microscopy
Exclusion criteria
Exclusion criteria: Anyone who has taken systemic or topical antifungals in the four weeks prior to initiation of study; or presents with solitary lesion, history of hypersensitivity to antifungals, on any systemic medications known to have interactions with itraconazole, or with superadded bacterial infections, pregnancy or lactating and on immunosuppressive drugs or with any immunosuppressive disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete cure: Clearance on microscopy, no residual signs & symptoms (Except Post inflammatory hyperpigmentation) Mild resolution: Upto 25% improvement Moderate resolution: 25-50% improvement Significant resolution: 51-99% improvementTimepoint: 0, 2 and 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects due to the medicationsTimepoint: 0, 2 and 4 weeks;Time of clinical cure and improvementTimepoint: 0, 2 and 4 weeks | — |
Countries
India
Contacts
Public ContactLt Col Dr Ruby Venugopal
Armed Forces Medical College, Pune, Maharashtra
Outcome results
None listed