To study the postoperative pain in patients of lower limb surgeries

To evaluate the postoperative analgesia of isobaric levobupivacaine alone compared with clonidine or nalbuphine under spinal anesthesia in patients of lower limb surgeries

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/08/027214

Enrollment

Registered

2020-08-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M849- Disorder of continuity of bone, unspecified

Interventions

Intervention1: Intrathecal drugs: groups will be compared with respect to onset and duration of sensory and motor blockade,duration of postoperative analgesia, sedation score, side effects and complic

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients undergoing lower limb surgeries 2. American Society of Anesthesiology (ASA) Grade I and II

Exclusion criteria

Exclusion criteria: 1.Neurological and musculoskeletal disease. 2.Patients with cardiovascular diseases. 3.Contraindications to regional anesthesia such as local infections/sepsis at the site of lumbar puncture, anatomical disorders of spine, shock, any bleeding disorder and patient on anticoagulants. 4.Hypersensitivity to study drugs 5.Pregnant women 6.History of opioid dependence

Design outcomes

Primary

Measure	Time frame
To evaluate the duration of postoperative analgesia of isobaric levobupivacaine alone compared with clonidine or nalbuphine under spinal anesthesia in patients of lower limb surgeries.Timepoint: pain will be assessed from 0 min till the 24 hours of the surgery	—

Secondary

Measure	Time frame
to evaluate the sedative and adverse effects of all the three drugs in the lower limb surgeriesTimepoint: effects will be assessed from 0 min till the 24 hours of the surgery	—

Countries

India

Contacts

Public ContactDr Balpreet Kaur

Sri Guru Ram Das Institute of Medical Sciences and Research

sgrdanaesthesia.academics@gmail.com9915530033

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026