FindTrial
Sign In

Comparison of the effect of depressive symptoms on the dose requirement during the start of anesthesia in patients undergoing surgery for cancerous and other non-cancerous conditions - A Prospective Observational Study

Presurgical depressive symptom severity and anesthesia response during induction in patients undergoing surgery for malignant and non-malignant conditions â?? A Prospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/08/027213
Enrollment
174
Registered
2020-08-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

None listed

Sponsors

JIPMER Intramural fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age > 18 years. 2. American Society of Anaesthesiologists (ASA) physical status I, II, and III. 3. Patients undergoing elective surgery for malignant and non-malignant non-neurological conditions.

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular compromise or an ejection fraction of 20%. 2. Allergy to Propofol . 3. Modified Mallampatti Score 3 or more.

Design outcomes

Primary

MeasureTime frame
To compare the difference in propofol required for induction of anesthesia in patients undergoing surgery for malignancy versus those undergoing surgery for non-malignant conditionsTimepoint: Dose required to attain a BIS value between 50-60 at the time of induction—

Secondary

MeasureTime frame
To compare the amount of inotrope/ vasopressor/ anesthetic agent/ opioid required to restore the altered hemodynamic response associated with induction, laryngoscopy and intubation in patients undergoing surgery for malignancy versus those undergoing surgery for non-malignant conditions.Timepoint: 2,4,6,8,10 minutes;To record the hemodynamic response at the time of induction, laryngoscopy and intubation in patients undergoing surgery for malignancy versus those undergoing surgery for non-malignant conditions.Timepoint: 2.4.6.8.10 minutes;3. To compare the difference in propofol required for induction of anesthesia in patients undergoing surgery for malignancy with a PHQ-9 score more than 9 versus those undergoing surgery for malignancy with a PHQ-9 score less than or equal to 9.Timepoint: Dose required to attain a BIS value between 50-60 at the time of induction—

Countries

India

Contacts

Public ContactViswanath Narayanan

JIPMER

sumanlatagupta13@gmail.com9488830091

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026