Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: Daily measurement of urinary and plasma renal biomarkers: Daily measurement of urinary and plasma renal biomarkers in a COVID-19 positive patients with moderate-severe respiratory sympt
Sponsors
AIIMS Patna
Eligibility
Inclusion criteria
Inclusion criteria: 1.RT PCR proved COVID-19 positive patients admitted in AIIMS Patna 2.Age 18-65 years 3.Clinical Category of Patients A.Mild category B.Moderate category C.Severe category
Exclusion criteria
Exclusion criteria: 1.Pre-existing AKI 2.Severe chronic kidney disease (CKD) with estimated glomerular filtration rate (e-GFR) 3.End-stage renal failure on regular dialysis 4.Kidney transplant within the last 12 months 5.Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Relation of these renal biomarkers with progression to any stage of acute kidney injury As defined by Kidney Diseases: Improving Global Outcome (KIDGO) Timepoint: For Milder group time points will be on Baseline 0 Day, 3rd Day and 10th Day or on the day of clinical deterioration For Moderate to severe group on Day 0 (baseline), 1st Day, 2nd Day,3rd Day, 5th Day,7th Day and 10th Day. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Relation of these renal biomarkers with the need for RRT in first 10 days. 2.Relation of these renal biomarkers with Mortality. 3.Relation of these renal biomarkers with serum level of IL-6 4.Relation of these renal biomarkers and conversion of mild group of patient to moderate or severe group. Timepoint: For mild group of patients: 0 Day (Baseline), 3rd Day and 10th Day or on the day of clinical deterioration. For moderate to severe group of patients: 0 Day (Baseline), 1st Day, 2nd Day,3rd Day, 5th Day,7th Day and 10th Day. | — |
Countries
India
Contacts
Public ContactNeeraj Kumar
All India Institute of Medical Sciences,Patna
Outcome results
None listed