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Comparison of the drug given by intravenous injection vs. drug given near spinal cord to provide pain relief to patient who has donated a part of liver for transplant into another patient.

Comparison of Intravenous Fentanyl based Patient Controlled Analgesia (PCA) vs Epidural Ropivacaine infusion for management of post-operative pain in live donor hepatectomy patients: A prospective observational study - IVFvsEPCA

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027158
Enrollment
108
Registered
2020-08-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K729- Hepatic failure, unspecified

Interventions

Intervention1: IV Fentanyl: IV FENTANYL infusion of 0.5mcg/kg/hr and PCA dose of 10mcg Intervention2: EPIDURAL ROPIVACAINE: EPIDURAL ROPIVACAINE INFUSION 0.2% @4-6ml/hr

Sponsors

Center for liver and Biliary Sciences Max Super Speciality Hospital SaketNew DelhiIndia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All healthy donors for donor hepatectomy. 2. Age > 18 yrs. 3. ASA I- II individuals

Exclusion criteria

Exclusion criteria: 1. Patient denying consent or preferring a specific mode of analgesia. 2. Vertebral Deformity / history of vertebral interventions. 3. Local site infections.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of analgesia of low thoracic epidural analgesia versus intravenous fentanyl patient control analgesia (PCA) till post-op day 3Timepoint: Post-op Day 3—

Secondary

MeasureTime frame
1) To document incidence of post-operative complications of epidural analgesia, namely: a. Dural Puncture and/or Post Dural Puncture Headache (PDPH) b. Hypotension c. Respiratory Depression 2) To evaluate the side effects of intravenous fentanyl infusion namely: a. Post-op Nausea Vomiting (PONV) b. Respiratory depression 3) To document any other post-op complication, its management, profiling the patients as per Clavein Dindo classification and comparison between the two groups. Timepoint: Post-op Day 3—

Countries

India

Contacts

Public ContactDr Shweta A Singh

Max Super Speciality Hospital

drshwetasingh29@gmail.com9810625177

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026