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Giving Oral Rehydration Solution to patients in preoperative period and observing its effect in reducing cardiac ischemia during Spinal Anaesthesia

Role of preoperative Oral Rehydration Solution in reducing cardiac ischemia during Spinal Anaesthesia: A prospective, randomized, interventional study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027149
Enrollment
126
Registered
2020-08-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Group A: Patients will receive 1000ml of preoperative Oral Rehydration Solution starting 10 PM after last meal, on the night prior to surgery and up to 2 hrs prior to initiation of Spin

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists grade I, II and III undergoing elective Total Knee Arthroplasty surgery under Spinal Anaesthesia

Exclusion criteria

Exclusion criteria: Patients requiring emergency surgery Inability to give consent Any contraindication to Spinal Anaesthesia Body Mass Index more than 35kg/square metre Evidence of ischemic changes in 12 lead ECG during pre-anaesthetic work up prior to surgery Known cardiac, renal disease or diabetes mellitus

Design outcomes

Primary

MeasureTime frame
Ischemic changes in 12-lead ECGTimepoint: 2 minutes,5 minutes, 10 minutes, 15 minutes, 30 minutes, after giving Spinal Anaesthesia, respectively—

Secondary

MeasureTime frame
Duration of fasting for solid and for clear fluidTimepoint: Preoperative period;Duration of surgeryTimepoint: Intraoperative period;Gastric volumeTimepoint: Before induction of Spinal Anaesthesia;Incidence of bradycardia, tachycardia, hypotension, hypertension and hypoxiaTimepoint: For first 30 minutes after giving Spinal Anaesthesia;Sensory level achievedTimepoint: 20 minutes after giving Spinal Anaesthesia;The Pleth variability index and perfusion indexTimepoint: 2 minutes, 5 minutes, 10 minutes, 15 minutes, 30 minutes, after giving Spinal Anaesthesia, respectively;Total blood lossTimepoint: Intraoperative period;Total IV fluid infusedTimepoint: Intraoperative period—

Countries

India

Contacts

Public ContactDr Gaurav Jain

All India Institute of Medical Sciences Rishikesh

gauravhld@gmail.com8808631209

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026