Health Condition 1: L80- Vitiligo Health Condition 2: L80- Vitiligo
Conditions
Interventions
Intervention1: 0.2% tacrolimus with excimer lamp is the intervention: placebo with excimer lamp is the control
Control Intervention1: 0.1% tacrolimus with excimer lamp is comparator: 27 patients is th
Sponsors
All India Institute of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Patients consenting to participate;able to visit hospital twice weekly for excimer and have ability to comprehend the different topical application on different patches with multiple or atleast three similar lesions of non-segmental vitiligo of more than 4 cm square size over non-glabrous skin,not developing new lesions or expansion of new lesions within past 2 months,not receiving any kind of systemic therapy for past one month and topical therapy for the past one week.
Exclusion criteria
Exclusion criteria: pregnant ,lactating mothers children less than 12 years active infection or bleeding at site Koebnerization for less than 1 month duration Lesions distal to wrist Patients with photosensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of percentage mean re-pigmentation of the representative vitiligo patches in the each arms by using graphical method, photographic assessment and visual analogue scaleTimepoint: Three months | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of blood levels of tacrolimus for systemic toxicity. Recording local and systemic adverse effects and comparing between three arms. Patient outcome over the course of the study by vis-22.Timepoint: Three months except blood tacrolimus levels at the end of one month of enrolling | — |
Countries
India
Contacts
Public ContactDr Gouri RP Anand
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed