Health Condition 1: H118- Other specified disorders of conjunctiva
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 18 years of age and above Newly diagnosed cases with symptomatic MGD mild to moderate(Stage 2 and 3) Meibomian gland area loss: nil to medium dropout on visual inspection of images analyzed by Lipiscan. Lipid layer thickness less than 100nm seen on Lipiview II. Providing written Informed Consent for Treatment
Exclusion criteria
Exclusion criteria: Patients having other ocular surface disorder e.g. steven johnson syndrome, ocular pemphigoid, chemical injury, limbal stem cell deficiency etc. (Plus disease) Patients undergoing any current treatment for MGD/ dry eye Patients with history of any ocular surgery in previous 3 months. Ocular injury within prior 3 months Ocular herpes of eye/eyelid within prior 3 months Active ocular infection Active ocular inflammation or history of chronic, recurrent ocular inflammation within prior 3 months Eyelid abnormalities that affect lid function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in ocular surface microbial flora after vectored thermal pulsation treatmentTimepoint: 1 month 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of vectored thermal pulsation treatment in Ocular symptoms(Ocular Surface Disease Index) Ocular surface and tear film stability(TBUT, Schirmer test, Tear osmolarity, Ocular surface staining) Visual acuity and quality(assessed using ray-tracing aberrometry) Correlation of change in conjunctival flora with clinical signs and symptoms of Meibomian gland dysfunction Timepoint: 1 month 3 months | — |
Countries
India
Contacts
All India Institute of Medical Sciences