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ANALYSIS OF VAGINAL FLUID ESTIMATION IN PREMATURE RUPTURE OF MEMBRANES

THE DETERMINATION OF THE ACCURACY OF VAGINAL FLUID LEVELS OF UREA AND CREATININE IN THE CLINICAL DIAGNOSIS OF RUPTURE OF FETAL MEMBRANES

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/08/027113
Enrollment
100
Registered
2020-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O411- Infection of amniotic sac and membranes

Interventions

Intervention1: collection of amniotic fluid: Within 24 hours after membrane rupture and before vaginal examination or administration of any drugs.Speculum is introduced and 3ml of amniotic fluid colle

Sponsors

Shri BMPatil Medical College Hospital and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Gestational age of 28-42 weeks Singleton pregnancy

Exclusion criteria

Exclusion criteria: 1.Vaginal spotting/ bleeding 2. Meconium in the vaginal fluid leak 3.Recent vaginal infection having history of use of vaginal drugs 4.Pregnant women with presence of regular uterine contractions 5. Multiple Pregnancy 6. Pregnant women with known medical and prenatal complications 7. Pregnant women with cohabitation in the prior night, and with fetal anomalies

Design outcomes

Primary

MeasureTime frame
Is increase in urea and creatinine cause of amniotic membrane ruptureTimepoint: In cases with premature rupture of membranes, within 24 hours sample is collected and in control cases after giving vaginal wash with Normal saline.The increase in urea and creatinine levels are estimated to rule out as a cause of amniotic membrane rupture

Secondary

MeasureTime frame
To estimate the levels of urea and creatinine in the wash of patients without membrane ruptureTimepoint: the estimation is done at the time of visit to our institution.To see relation between the levels of urea and creatinine in normal patients and those with vaginal fluid

Countries

India

Contacts

Public ContactDr Aruna Biradar

Shri. B.M.Patil Medical College Hospital and Research Centre

aruna.biradar@yahoo.com8197191472

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026