Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: Colchicine tablet: Patients in this group will be given tablet colchicine at a loading dose of 1 mg followed by 0.5 mg oral thrice a week for 6 months and standard care for ESRD as rou
Sponsors
Dr Krishna Kishore C
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients between 18 to 65 years of age of either gender with end stage renal disease on regular dialysis 2.Willing to give informed consent
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women 2.Patients on CYP3A4 inhibitors and P- glycoprotein inhibitors 3.Patients with known blood dyscrasias such as myelosuppression, leukopenia, granulocytopenia, thrombocytopenia and aplastic anemia 4.Patients with Hepatitis B, ,Hep.C positive status and liver disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Feasibility outcomes will be time taken to recruit 100 patients and compliance for colchicine 2.Safety outcome includes treatment emergent adverse effects due to study drug and cessation of study drug due to adverse events 3. Efficacy outcome includes incidence of COVID infection between the 2 groups. Timepoint: 6 Months | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDrAlben Sigamani
Mazumdar Shaw Medical Center, Narayana Health city
Outcome results
None listed