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Comparision of two doses of a medicine for treating acute asthma attack in children between age of 2 to 5 years

Comparison of two doses of intravenous magnesium sulphate in improving the clinical outcome of children 2 to 5 years of age with acute severe asthma - a Pilot Randomized Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027064
Enrollment
20
Registered
2020-08-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J459- Other and unspecified asthma

Interventions

Intervention1: Magnesium sulphate: 50 mg per kg dose intravenous magnesium sulphate over 30 minutes once Control Intervention1: Magnesium sulphate: 25 mg per kg per dose intravenous over 30 minutes o

Sponsors

Jawaharlal Institute of Pondicherry Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children with acute severe asthma with PRAM score 8 or more and continue to be 8 or more one hour post intervention

Exclusion criteria

Exclusion criteria: Clinical suspicion of pneumonia Acute kidney injury or hypotension Congenital heart disease and structural airway anomalies that produce wheeze

Design outcomes

Primary

MeasureTime frame
Proportion of children in whom intensive care admissions are preventedTimepoint: During period of hospitalization for study half an hour, two hours, four hours—

Secondary

MeasureTime frame
Side effects of intravenous magnesium sulfate in above age group.Timepoint: During hospital stay.;To correlate serum magnesium levels to the amount of magnesium sulphate infused and clinical outcomeTimepoint: one hour Before and one hour after injecting magnesium—

Countries

India

Contacts

Public ContactChakicherla Sai Monica

Jipmer

cvenkatesh@hotmail.com9842534154

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026