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A study to compare efficacy of isotretinoin and salicylic acid plus mandelic acid peel versus isotretinoin alone in the treatment of acne tarda

A Randomized prospective study comparing low dose isotretinoin alone with combination of low dose isotretinoin and salicylic acid plus mandelic acid peel in the treatment of acne tarda

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027055
Enrollment
60
Registered
2020-08-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L709- Acne, unspecified

Interventions

Intervention1: Isotretinoin 20 mg and salicyclic acid plus mandelic acid peel: Isotretinoin 20 mg once daily for a period of 3 months and salicylic acid plus mandelic acid peel once monthly Control In

Sponsors

Ims and sum hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All female patient clinically diagnosed with acne tarda of all grades in age group of 25 to 45 yrs

Exclusion criteria

Exclusion criteria: Pregnancy and lactation, planning to pregnancy, history of hypertropic scarring and keloid , history of known hypersensitivity to salicylic acid, history of drug intake ( antidepressant, antiepileptics, steroid)

Design outcomes

Primary

MeasureTime frame
Efficacy of isotretinoin and salicylic acid plus mandelic acid peel, acne severity index , acne grading, side effect assessmentTimepoint: Efficacy to be evaluated at 4 week, 8 week, 12 week and 16 week—

Secondary

MeasureTime frame
Hormonal evaluationTimepoint: Hormonal evaluation at starting of treatment and assessment of correlation at 16 weeks—

Countries

India

Contacts

Public ContactDr Ajaya Kumar jena

Ims and sum hospital

ajayajena@soa.ac.in9437909933

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026