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A clinical study to compare two techniques of pain relief(intravenous through blood route vs epidural through a catheter in back) after surgery for cancer treatment using reduction of tumour mass and chemotherapy at high temprature

A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy â?? prospective randomized control study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027052
Enrollment
50
Registered
2020-08-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C18- Malignant neoplasm of colon Health Condition 2: C56- Malignant neoplasm of ovary Health Condition 3: C25- Malignant neoplasm of pancreas Health Condition 4: C20- Malignant neoplasm of rectum Health Condition 5: C17- Malignant neoplasm of small intestine Health Condition 6: C16- Malignant neoplasm of stomach

Interventions

Intervention1: Intravenous local anaesthetic and opioid infusion: Bolus dose of 1.5 mg/kg lignocaine over 15 mins, starting approximately 15 mins before surgical incision and fentanyl 0.5 mcg/kg, appr

Sponsors

Dr BRAIRCH AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Posted for CRS and HIPEC surgery. 2. Agree to participate in the study and have signed written informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated with mental illness, severe heart disease (NYHA classification >=3), any renal or hepatic disorder before surgery. 2. Contraindications of epidural anesthesia. 3. Allergic to any drug used during the study.

Design outcomes

Primary

MeasureTime frame
To evaluate postoperative analgesic efficacy of the analgesic technique.Timepoint: Immediately after extubation, 1 hour, 2 hour, 4 hour, 8 hour, 12 hour, 18 hour and 24 hour.—

Secondary

MeasureTime frame
To evaluate analgesic requirement intraoperatively.Timepoint: Intraoperatively every 10 minutes requirement of analgesia will be seen and total dose of fentanyl used will be noted.—

Countries

India

Contacts

Public ContactDr Kiran Mahendru

Dr BRAIRCH AIIMS New Delhi

drrgarg@hotmail.com9810394950

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 10, 2026