Study to assess effects of nano ozonised hydrogen peroxide nebulisation on results of RT-PCR for novel corona Virus thus infectivity and clinical course among mild to moderate sick COVID-19 Patients

A Prospective ,randomized ,double blind,placebo controlled study to access effects of nano ozonized hydrogen peroxide nebulization on results of RTPCR for noval corona virus thus infectivity and clinical course among mild to moderate sick Covid 19 patients HOPE in Covid 19(Hydrogen Peroxide Inhalation).

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/08/027038

Enrollment

100

Registered

2020-08-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

Intervention1: Triozone: 1 ml of trio zone mixed with 4 ml of normal saline given 3 times a day from nasal route . a cumulative 5ml single dose is used for nebulisation by nasal route once a day .

Eligibility

Inclusion criteria

Inclusion criteria: All newly diagnosed patients Not requiring mechanical ventilation on oxygen therapy Tolerating hydrogen peroxide nebuliser Consenting patients On same treatment protocol

Exclusion criteria

Exclusion criteria: Patients not giving consent Patient not tolerating nebulization

Design outcomes

Primary

Measure	Time frame
Proportion of patients who turned negative on RT-PCR for for nCOV for two consecutive days.Timepoint: 6 month	—

Secondary

Measure	Time frame
Worsening of patient who turned negative on RT-PCR for nCoV for two consecutive days Patients remain positive even after 5 days of adequate nebulisation Patients showing any manifestation of ADR to izonized hydrogen peroxide.Timepoint: 6 MONTH	—

Countries

India

Contacts

Public ContactDrAshish Gautam

S N Medical College

ppagrawal120@gmail.com9319250485

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026