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comparison of two drugs for prevention of post operative nausea and vomiting

To compare the efficacy of palonosetron dexamethasone combination with palonosetron and dexamethasone alone for prevention of post operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/08/027031
Enrollment
75
Registered
2020-08-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: inj.palonosetron and inj. dexamethasone: Group A will receive 0.075 mg inj. palonosetron along with 8mg of inj. dexamethasone Group B will receive 0.075 mg of inj. palonosetron Grou

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to ASA grade 1 and 2. Patients posted for elective laparoscopic cholecystectomies under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patient refusal. Patients with known hypersensitivity or contraindications to study drugs. Patients posted for emergency surgery. Patients with history of nausea, vomiting or retching in 24 hours before anaesthesia. 5. Patients receiving antiemetic therapy in 24 hours before surgery. 6. Patients with history of motion sickness. 7. Pregnant female.

Design outcomes

Primary

MeasureTime frame
postoperative nausea and vomiting in patients undergoing elective laparoscopic cholecystectomies under general anaesthesia. Timepoint: one hourly for the first four hours then at 8, 12, 18,24,30,36,42,48 hours—

Secondary

MeasureTime frame
NATimepoint: NA—

Countries

India

Contacts

Public ContactDr Chanpreet Kaur

SGRDIMSAR

kumarianitadr1@gmail.com9815632909

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026