Health Condition 1: R652- Severe sepsis
Conditions
Interventions
Intervention1: Intravenous Immunoglobulin: Human Normal Immunoglobulin 5 % solution(5gm/100ml)b.Brand Name - GLOBUCEL
Content:Total Protien 50 gm/dl
immunoglobulin G 95%
Maltose- 100gm/L
Sponsors
MLN Medical College Prayagraj Uttar Pradesh
Eligibility
Inclusion criteria
Inclusion criteria: 1.Neonates with clinical signs of sepsis and positive sepsis screen. 2.Neonates with positive blood culture. 3.Neonates with septic meningitis diagnosed on basis of biochemical and microbiological examination or CSF culture.
Exclusion criteria
Exclusion criteria: 1.All neonates whose attendants did not give consent for IVIG administration. 2.All neonates whose attendants who did not give consent to involve in Study. 3.All neonates with major congenital malformation. 4.All neonates with known metabolic disease. 5.Neonates in shock or require positive pressure ventilation at the time of admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of days of admission in hospitalTimepoint: 7 days and 30 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality rate. Weight gain during hospital course Need for ventilation. Number of days of Oxygen requirement. Development of necrotizing enterocolitis. Side effects of IvIg. Timepoint: 1day and 30 days | — |
Countries
India
Contacts
Public ContactDr Mohammad Qaim Rizvi
Motilal Nehru Medical College
Outcome results
None listed