Health Condition 1: M511- Thoracic, thoracolumbar and lumbosacral intervertebral disc disorders with radiculopathy
Conditions
Interventions
Intervention1: Tablet Pregabalin: Oral tablet Pregabalin 75 mg two times a day for 30 days will be given
Control Intervention1: tablet Ibuprofen: Oral Tablet Ibuprofen 400 mg two times a day for 30 da
Sponsors
Mahatma Gandhi Institute of medical sciences sevagram wardha
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient having lumbar disc herniation on MRI lumbar spine 2. Patient between age 20 to 60 years 3. The duration of symptoms should be less than 14 days. 4. Neuropathic Pain-Screening Questionnaire developed by Ogawa et al will be used and only those patients who have score of greater than 5 will be included in the study. 5. Patient giving consent for treatment.
Exclusion criteria
Exclusion criteria: 1. Patient with significant motor weakness, myelopathy signs, bowel or bladder involvement 2. Pathology involving vertebral body (tumor, fracture) 3. Previous spine surgery 4. Patient having renal dysfunction, ischemic heart disease, previous intolerance to NSAIDS or Pregabalin, psychiatric disorder. 5. Pregnant or Breastfeeding mother
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient will be evaluated at 0, 2 and 4 weeks using Visual analogue scale pain score, Revised Oswestry disability index, and Patient Global impression of change (PGIC) score, Clinical global impression of change score.Timepoint: base line (i.e on first day), 2 weeks and 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale sleep score.Timepoint: measured at 0, 2 and 4 weeks | — |
Countries
India
Contacts
Public ContactDr Prasheelkumar Gupta
Mahatma Gandhi Institute of Medical Sciences, Sevagram
Outcome results
None listed