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Best medicine to induce labour in Intra uterine death of fetus

Efficacy of Mifepristone in inducing labour in Intra uterine death- a Randomized Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026912
Enrollment
62
Registered
2020-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O359- Maternal care for (suspected) fetal abnormality and damage, unspecified

Interventions

Intervention1: Mifepristone with standard treatment of Misoprostol for inducing labour in Intrauterine death: Mifepristone (RU-486) is an antiprogesterone drug which binds to progesterone receptor wit

Sponsors

Government Institute of Medical SciencesGreater Noida Gautam Buddha Nagar UP
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A. Inclusion criteria : Confirmed IUD Singleton pregnancy Cephalic presentation Bishops score Previous normal vaginal deliveries No cephalopelvic disproportion

Exclusion criteria

Exclusion criteria: Grand Multipara Previous LSCS Pre eclampsia Abruption PROM, Sepsis DIC Contraindications to mifepristone & misoprostol

Design outcomes

Primary

MeasureTime frame
induction to delivery interval (interval between first dose of misoprostol and delivery).Timepoint: induction to delivery interval (interval between first dose of misoprostol and delivery).

Secondary

MeasureTime frame
mode of deliveryTimepoint: vaginal or cesarean;adverse effectsTimepoint: nausea, vomiting, diarrhea, fever, shivering;change in the Bishops score, change in the Bishops scoreTimepoint: 6-13 in 24 hours or less;number of doses of misoprostol requiredTimepoint: 0-5 doses;requirement of oxytocinTimepoint: mIU/ml

Countries

India

Contacts

Public ContactDr Ritu Sharma

Government Institute of Medical Sciences, Greater Noida

drritu661@gmail.com9717001590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026