Health Condition 1: J969- Respiratory failure, unspecified
Conditions
Interventions
None listed
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients consenting for the study 2. Patients mechanically ventilated for more than 48 hours. 3. All patients considered eligible for a SBT by the attending physician as per standard ICU protocol: FiO2 200, respiratory rate
Exclusion criteria
Exclusion criteria: 1. Patients on short term mechanical ventilation in the immediate postoperative period. 2. Patients aged 3. Patients with spinal cord injury above T8 level 4. Presence of significant cardiac arrhythmia 5. Patients with diaphragmatic paralysis 6. Patients planned for prophylactic noninvasive ventilation after extubation. 7. Patients in whom a suitable ultrasonographic image could not be obtained for lung, diaphragm and cardiac measurements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To assess if the thoracic fluid content (TFC) measured at the beginning of SBT by cardiometry can predict weaning success or failure. Timepoint: To Assess before spontaneous breathing trial and within 48hours of spontaneous breathing trial | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To assess if the lung ultrasound score, echocardiographic parameters and NT Pro BNP measured before SBT either alone or in combination can predict weaning failure. 2.To assess the correlation between TFC and extravascular lung water index(EVLWI) Timepoint: To Assess before spontaneous breathing trial and within 48hours of spontaneous breathing trial | — |
Countries
India
Contacts
Public ContactRahul kumar Anand
All India Institute of Medical Sciences
Outcome results
None listed