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Does addition of biological agents enhance the take up rate of fat plug graft for repair of perforated eardrum?

Graft take-rate for Fat Graft Myringoplasty versus Platelet Rich Plasma enriched Fat Graft Myringoplasty versus Hyaluronic acid enriched Fat Graft Myringoplasty in patients of Mucosal COM in a tertiary care centre: A randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026812
Enrollment
66
Registered
2020-07-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H902- Conductive hearing loss, unspecified

Interventions

Intervention1: PRP and HA enriched Fat graft Myringoplasty: 1.The patient will be taken up surgery. Under local infiltration fat graft will be taken from the sites like ear lobule / back of ear / abdo

Sponsors

Nivedhan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with inactive mucosal disease with small (Grade-I) and medium (Grade-II) sized perforation (Salibaâ??s classification). 2.No ossicular pathology.

Exclusion criteria

Exclusion criteria: 1.Perforation of grade III or more. 2.PTA of more than 45 dB or with mixed hearing loss

Design outcomes

Primary

MeasureTime frame
Graft take - rate (Salibaâ??s grading) Timepoint: At 6th week and 3rd month post operative period.—

Secondary

MeasureTime frame
1.Hearing gain reporting. Timepoint: At 6th week and 3rd month post operative period.—

Countries

India

Contacts

Public ContactDr Madhu Priya

AIIMS, Rishikesh

drpriyamadhu@gmail.com9751003933

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026