Health Condition 1: K229- Disease of esophagus, unspecified Health Condition 2: K319- Disease of stomach and duodenum, unspecified Health Condition 3: K23- Disorders of esophagus in diseasesclassified elsewhere Health Condition 4: K269- Duodenal ulcer, unspecified as acute or chronic, without hemorrhage or perforation Health Condition 5: K209- Esophagitis, unspecified Health Condition 6: K30- Functional dyspepsia Health Condition 7: K259- Gastric ulcer, unspecified as acute or chronic, without h
Conditions
Interventions
Intervention1: Glycopyrrolate: 1 ml containing 0.2 mg diluted in 1 ml 0.9% saline intravenous route over 1 minute
Control Intervention1: Placebo: 2 ml 0.9% normal saline intravenous over 1 minute
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18-60 years, undergoing unsedated diagnostic upper GI endoscopy
Exclusion criteria
Exclusion criteria: a. History of glaucoma b. Known cardio respiratory disease c. Persons with chronic constipation d. History of obstructive urinary disorders e. Prior gastrectomy f. Persons taking anti-anxiety medications g. Pregnancy h. History of prior upper GI endoscopy i. Active upper respiratory infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess effect of premedication with glycopyrrolate on the level of patient tolerance during unsedated upper GI endoscopyTimepoint: 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To study the cardio - respiratory fluctuations during unsedated upper GI endoscopy 2. To study the effect of premedication on the duration of unsedated upper GI endoscopy 3. To assess the number of failed endoscope intubations and incomplete endoscopies 4. To calculate the Endoscopistâ??s assessment score after the unsedated upper GI endoscopy Timepoint: 60 minutes | — |
Countries
India
Contacts
Public ContactRamalingam R
JIPMER
Outcome results
None listed