Health Condition 1: E113- Type 2 diabetes mellitus with ophthalmic complications
Conditions
Interventions
None listed
Sponsors
Dr Nikhil Gopalakrishnan
Eligibility
Inclusion criteria
Inclusion criteria: - Type 1 or Type 2 Diabetic Patients aged 18 or more, with coexisting Chronic Kidney Disease due to Diabetes (Diabetic Nephropathy). - Centre involving Diabetic Macular Edema defined as baseline SD-OCT central subfield thickness of 320 microns in men and 305 microns in women.
Exclusion criteria
Exclusion criteria: - Patients with Chronic Kidney Disease due to etiology other than Diabetic Nephropathy - Patients with Macular Edema or any retinal pathology due to causes other than Diabetes. - Patients with significant media opacities hindering accurate OCT assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To study the effect of Hemoglobin on presence and severity of Diabetic Macular Edema in the setting of Chronic Kidney Disease. 2.To identify OCT biomarkers or patterns in Diabetic Macular Edema, which are specific for patients with Chronic Kidney Disease i.e., Diabetic Nephropathy associated retinal changes. Timepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the role of renal parameters such as Proteinuria (Microalbuminuria), Serum Urea, Serum Creatinine and GFR on presence and severity of Diabetic Macular EdemaTimepoint: 2 years | — |
Countries
India
Contacts
Public ContactDr Sudha Menon
O.E.U. Institute of Ophthalmology
Outcome results
None listed