Health Condition 1: E236- Other disorders of pituitary gland
Conditions
Interventions
None listed
Sponsors
Department of Endocrinology
Eligibility
Inclusion criteria
Inclusion criteria: Male Patients with CHH with cryptorchidism, unilateral or bilateral. The diagnosis of CHH was based on the following criteria: (1) Clinical Phenotype- Unilateral or bilateral cryptorchidism with micropenis since birth AND (2) Evidence of CHH based on 1 of the following criteria a) Age > 14 years with absence of secondary sexual characters with low or normal gonadotropins along with low Inhibin B and Testosterone for age b) clinical history of anosmia/hyposmia and/or MRI Pituitary showing hypoplasia / aplasia of olfactory bulbs and sulci c) Genetic analysis conducive with CHH d) Syndromic etiology with CHH as a component AND 3) Normal levels of other pituitary hormones 4) Absence of any structural lesions on imaging (MRI) of brain
Exclusion criteria
Exclusion criteria: Idiopathic cryptorchidism or cryptorchidism of any etiology other than CHH.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Testicular volume and descent,Penile length, Hormonal response: Inhibin-B,Testosterone Spermatogenesis and fertilityTimepoint: 3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Spermatogenesis and fertilityTimepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Tushar Bandgar
Seth G.S.Medical college and KEM hospital
Outcome results
None listed