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Comparison of pre-surgical and post-surgical antibiotic therapy following surgical removal of lower third molar

Comparison of pre-surgical and post-surgical antibiotic therapy following lower third molar disimpaction

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026722
Enrollment
30
Registered
2020-07-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Pre surgical parenteral antibiotic: Commercially available Inj.Amoxicillin 1gm, 1 hour before the procedure Control Intervention1: Post surgical oral antibiotic: Commercially available

Sponsors

ARYA ANIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Both male and female patients with bilaterally impacted mandibular third molars Systemically healthy patients who had not undertaken antibiotics or anti-inflammatory drugs within 2 weeks before the procedure Patients who are willing to give their consent for their participation in the study

Exclusion criteria

Exclusion criteria: Patients presenting with local pathology- cyst/tumor associated with 3rd molar Patients with other systemic illness and immuno-compromised patients Allergic to amoxicillin Pregnant patients Patients presenting with abscess or cellulitis Non compliance of patient intaking post operative medication Known allergy to lignocaine Inability to appear for follow up

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness of conventional post operative antibiotic therapy with pre operative intravenous antibiotic therapy in patients undergoing lower third molar surgeryTimepoint: 3,7,14 days

Secondary

MeasureTime frame
To compare the variable of surgical site infection and alveolar osteitis among both groupsTimepoint: 3,7,14 days

Countries

India

Contacts

Public ContactDr Arya Anil

JSS Dental College and Hospital

drsathish75@gmail.com9845310737

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026