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A STUDY TO COMPARE THE EFFECTS BETWEEN DEXMEDETOMIDINE AND ESMOLOL TO REDUCE THE BLOOD PRESSURE, INTURN DECREASING THE BLOOD LOSS DURING SURGERIES OF NOSE AND TO FIND OUT WHICH AMONGST THESE TWO IS SAFE AND BETTER.

COMPARATIVE STUDY OF EFFECT OF LOW DOSE DEXMEDETOMIDINE INFUSION WITH THAT OF LOW DOSE ESMOLOL INFUSION ON INTRAOPERATIVE HEMODYNAMICS, ANESTHETIC REQUIREMENTS AND RECOVERY PROFILE IN PATIENTS UNDERGOING NASAL SURGERIES â?? A DOUBLE BLIND RANDOMIZED STUDY IN TERTIARY CARE CENTRE.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026711
Enrollment
60
Registered
2020-07-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M950- Acquired deformity of nose

Interventions

Intervention1: induced hypotension: Inducing controlled hypotension using low dose Dexmedetomidine 0.3mcg/kg bolus and 0.3mcg/kg/hr infusion and esmolol 0.3mg/kg bolus and 0.03mg/kg/hr infusion to red

Sponsors

SAPTHAGIRI INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American society of anaesthesiologists (ASA) grade 1 and 2 patients aged 20-50 years undergoing nasal surgeries under general anaesthesia 2.Patients willing to give consent

Exclusion criteria

Exclusion criteria: 1.Pregnant women 2.Allergy to the study drugs 3.Morbidly obese patients with body mass index (BMI) >30 kg/m2

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of low dose dexmedetomidine infusion with that of low dose esmolol infusion on the intraoperative hemodynamic profile, blood loss during surgery and emergence from anesthesia.Timepoint: Maintaining Mean arterial pressure of 65-70mmHg throughout the surgery and measuring once every 5 minutes for the initial 20 minutes and once every 10 minutes thereafter—

Secondary

MeasureTime frame
To evaluate the effect of these infusions on intraoperative anesthetic and analgesic requirements.Timepoint: Concentration of sevoflurane in % recorded once every 5 minutes for initial 20 minutes and once every 10 minutes thereafter—

Countries

India

Contacts

Public ContactSHRIDEVI GUDI

SAPTHAGIRI INSTITUTE OF MEDICAL SCIENCES, BENGALURU

drashwinih@rediffmail.com8971265579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026