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Pain relief in total knee replacement

Analgesic efficacy of adductor canal block (single shot + continuous infusion) versus epidural infusion in patients undergoing unilateral total knee arthroplasty

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026704
Enrollment
42
Registered
2020-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Epidural versus adductor canal catheter: In 21 patients pain relief will be via epidural infusion continuous for 48 hours and in other 21 via adductor canal catheter single shot 10 ml +

Sponsors

Ruby Hall Clinic
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Belonging to ASA 1 and 2 undergoing unilateral arthropathy

Exclusion criteria

Exclusion criteria: a) Patients refusiong to give their consent for the study b) Patients refusing Regional Anaesthesia/ or to have any continuous catheters in their body c) Patients having absolute or relative contra- indications to Regional Anaesthesia d) Patients having a revision TKR e) History of neurological abnormality in the operating leg eg. History of chronic pain, stroke or previous nerve injury f) Allergy or any contra- indication to drugs used in this study g) Morbidly obese ( BMI > 40 ) h) History of alcohol or drug abuse

Design outcomes

Primary

MeasureTime frame
assess analgesic efficacy by noting the VAS score at rest and on movement postoperativelyTimepoint: 0 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, 48 hrs

Secondary

MeasureTime frame
1) Ability to do straight leg raising test suggestive of motor or sensory block as a consequence of ACB or EA 2) Time to first successful ambulation 3) Time to first self micturition in ACB group (as EA group patients catheterized) 4) Analgesics used over 48 hours as a part of multimodal analgesic regimen in both groups 5) adverse events observed in either group 6) Length of hospital stay and 7) Chronic pain at 6 months follow up Timepoint: 0 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, 48 hrs

Countries

India

Contacts

Public ContactDr Tasnim Hozefa Karachiwala

Ruby Hall Clinic

drtasnim.u@gmail.com9860893851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026