Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Comparison of intravenous infusion of ketamine with placebo for postoperative analgesia: Intraoperative intravenous infusion of subanesthetic doses of ketamine for patients undergoing s
Sponsors
Rajarajeswari Medical college and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: American society of Anesthesiologists (ASA) â? and â?¡ of either sex Patients undergoing lumbar spine surgeries under general anaesthesia. Aged between 18 to 65 years Valid informed/explained consent
Exclusion criteria
Exclusion criteria: Patient with high risk coronary or vascular disease Patient with hepatic dysfunction Patient with history of psychosis Patient with elevated intracranial pressure or traumatic brain injury Patient with uncontrolled hypertension
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To evaluate side effects of subanaesthetic dose of ketamine. Timepoint: postoperative upto 24 hours | — |
Primary
| Measure | Time frame |
|---|---|
| (a) To evaluate the effectiveness of subanesthetic dose of ketamine in postoperative analgesia in patients undergoing single level discectomy under general anesthesia. (b) To evaluate the effectiveness of subanesthetic dose of ketamine to determine opioid sparing effectTimepoint: (a) To evaluate the effectiveness of subanesthetic dose of ketamine in postoperative analgesia in patients undergoing single level discectomy under general anesthesia and To evaluate the effectiveness of subanesthetic dose of ketamine to determine opioid sparing effect at predetermined time intervals - 1,2,4,6,12 and 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactDr ShubhaMR
Rajarajeswari medical college and hospital
Outcome results
None listed