To compare the effectiveness of vapocoolant spray(ethylchloride spray) and EMLA cream in reducing pain while inserting IV cannula in adult population

Comparison in the effectiveness of vapocoolant spray and EMLA cream in reducing pain of intravenous cannulation in adult population

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/07/026656

Enrollment

140

Registered

2020-07-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: EMLA cream in iv cannulation: to assess hemodynamic status and vas score while using topical emla cream 45 to 60 minutes prior iv cannulation Control Intervention2: Vapocoolant

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I, II, III and elective patients.

Exclusion criteria

Exclusion criteria: Patientâ??s refusal History of allergy to local anesthetics Oriented patients able to explain nature and extent of pain H/o peripheral neuropathy Local skin infection.

Design outcomes

Primary

Measure	Time frame
Comparing the pain reduction offered by Vapocoolant spray with respect to EMLA cream using VAS scoreTimepoint: Vapocoolant spray - 10 seconds after application EMLA cream- 30 to 45 minutes after application	—

Secondary

Measure	Time frame
To compare the pre and post procedure hemodynamics(Heart Rate, Plethysmography, Mean Arterial Pressure) between the two groups Timepoint: Baseline , 5 mins , 10 mins , 15 mins;To compare which of the methods is more cost effective in terms of Rupees Timepoint: Determined post procedure	—

Countries

India

Contacts

Public ContactSisla Nazer Puttan Purakkal

KMC Hospital

drranjanrao@gmail.com9449837154

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026