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A clinical study to compare the effects of two drugs Lignocaine and Magnesium sulfate for cardiovascular response to Laryngoscopy and endotracheal intubation.

Attenuation of cardiovascular response to laryngoscopy and endotracheal intubation: comparative evaluation of IV magnesium sulfate (20mg/kg) Vs IV lignocaine (1.5mg/kg)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026637
Enrollment
60
Registered
2020-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: iv MgSo4 20mg/kg: ATTENUATION OF CARDIOVASCULAR RESPONSE TO LARYNGOSCOPY AND INTUBATION Dose 20 mg/kg Drug given intravenously as premedication 20 minutes before giving general anaest

Sponsors

MEDICAL COLLEGE SUPPLY
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENT REQUIRING GENERAL ANEAESTHESIA UNDER ASA GRADING I AND II

Exclusion criteria

Exclusion criteria: KNOWN HYPERTENSIVES POOR LEFT VENTRICULAR FUNCTION EMERGENCY SURGERY DIABETICS DIFFICULT AIRWAY IMPAIRED RENAL FUNCTION AND ELECTROLYTE IMBALANCE

Design outcomes

Primary

MeasureTime frame
Attention of cardiovascular responses such as Heart rate and Blood pressure after Laryngoscopy and tracheal intubation. Timepoint: First five minutes after Laryngoscopy and tracheal intubation.—

Secondary

MeasureTime frame
Hemodynamic stability at the start of the surgery.Timepoint: Fifteen minutes after induction of general anaesthesia.—

Countries

India

Contacts

Public ContactSARAVANAN V K

BJMC AHMEDABAD

monalramani@yahoo.co.in9824758295

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026