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Effects of metoprolol , atenolol tablets in patients undergoing gall bladder removal operation

Effects of oral metoprolol and atenolol on analgesic and anesthetic requirements in laparoscopic cholecystectomy: a prospective randomized double blind placebo controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026617
Enrollment
78
Registered
2020-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: DRUG RESPONSE to tablet metoprolol: Patients will receive tablet metoprolol 50 mg [ 0.83 mg/kg] orally 90 minutes before surgery Control Intervention1: DRUG RESPONSE to tablet atenolo

Sponsors

SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES TIRUPATI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients undergoing elective laparoscopic cholecystectomy under general anesthesia. 2)Patients aged 18-60 years. 3)Patients of either sex. 4)Patients belonging to American Society of Anesthesiologists physical status I,II

Exclusion criteria

Exclusion criteria: 1)Patients allergic to study drugs. 2)Patients with severe cardiovascular, renal and respiratory co-existing diseases 3)Patients unwilling to participate in the study. 4)Patients unable to give informed consent. 5)Patients who are on beta blockers. 6)Hypertensive patients on treatment 7)Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
To study the intraoperative requirements of anesthesia and analgesiaTimepoint: 15 MINUTES

Secondary

MeasureTime frame
To compare the intraoperative hemodynamic parameters of the patientsTimepoint: 15 MINUTES

Countries

India

Contacts

Public ContactAKKIRAJU APARNA

SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES

drmhraosvims1957@gmail.com9493547651

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026