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Effects of nitroglycerine given during operation on kidney function after transplantation

Effects of nitroglycerin to post transplant renal function in kidney transplantation: A randomised trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026596
Enrollment
30
Registered
2020-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Nitroglycerine: Nitroglycerine is prepared as 50 ml aliquots diluted in normal saline to 100 microgram/ml given as single dose,slow bolus via renal artery over 10 minutes allowing up t

Sponsors

Dr Hashdeep Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing kidney transplant surgery after giving consent for this study

Exclusion criteria

Exclusion criteria: Patients who are at high cardiac risk as determined during cardiology clearance in the pre-transplant period, Fail to follow thesis protocol, Require a relook surgery of the transplanted kidney within the duration of the study, Patients with graft loss within the study period, Patients who require administration of nitroglycerine to treat other medical conditions such as angina, cardiac failure or severe hypertension during the study period and Patients who require the use of papaverine to relieve renal vasospasm.

Design outcomes

Primary

MeasureTime frame
Serum cystatin C and plasma malondialdehydeTimepoint: Within 24 hours

Secondary

MeasureTime frame
Creatinine levelTimepoint: 1 month

Countries

India

Contacts

Public ContactDr Deepesh Benjamin Kenwar

PGIMER, Chandigarh

harshdeep2209@gmail.com9899789776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026