Skip to content

Effect Of Topical Aerosolized Ropivacaine(0.75%)on Response To Extubation

Effect Of Topical Aerosolized Ropivacaine (0.75%) On Response To Extubation InAdults Patients Requiring General Anaesthesia For Elective Surgical Procedures : Randomized Controlled Trial - TAR

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026563
Enrollment
90
Registered
2020-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Atomization: Atomization of ropivacaine 0.75% 6 ml over glottis with atomizer instrument. Control Intervention1: Compare: Compare the response of drug with normal saline 6 ml by using

Sponsors

DrNaresh Yerne
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA PS I or II schedule, for elective surgery under general anaesthesia requiring oral endotracheal intubation with the clinically normal airway.

Exclusion criteria

Exclusion criteria: Severe cardiovascular, liver, and kidney disfunction; Allergies to amide local anesthetics; Patient with history of risk factor for perioperative aspiration of gastric ontents Difficult airway or history of maxillofacial and neck surgery; Chronic respiratory disease such as chronic obstructive pulmonary disease or asthma, recent respiratory tract infection, chronic cough, and current smoking. Patients with reoperation because of serious adverse events such as bleeding, Anesthesia time more than 4 h, and delayed extubation (more than 1 h without extubation) Prolong surgery (more than 3 hr) Transferd to the Intensive Care Unit (ICU) with the tube were eliminated. Medications invoving angiotensin converting enzyme inhibitor Refusal to participate in study

Design outcomes

Primary

MeasureTime frame
1.Hemodynamic response(Mean arterial pressure & HeartRate)toextubation; & 2.Cough occurring at extubation. Timepoint: Will be assesed at extubation After 2 min After 5 min

Secondary

MeasureTime frame
NoneTimepoint: None

Countries

India

Contacts

Public ContactDrAnjali Savargaonkar

Government Medical College;Nagpur

anj123sg@yahoo.com9527002761

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026