Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: PICOVRID syrup along with standard care: PICOVRID syrup 10 ml once a day along with standard care for 14 days
Control Intervention1: Standard care: Standard care for 14 days
Sponsors
Indian Institute of Technology Bombay
Eligibility
Inclusion criteria
Inclusion criteria: 1. Individuals COVID-19 positive in last 3 days 2. Patients with mild COVID-19 illness as defined in the MOHFW guidelines i.e. fever and or upper respiratory tract infection ,influenza like illness 3. Patients agreeing to provide a written informed consent 4. Patients who agree to reside in the COVID 19 facility during the study
Exclusion criteria
Exclusion criteria: 1. Patients with moderate or severe COVID 19 at the time of recruitment 2. Patients not able to consume drugs orally 3. Patients with uncontrolled hypertension or diabetes mellitus 4. Patients with decompensated liver disease or renal disease 5. Pregnancy or lactation 6. Patients with multiorgan failure 7. Patients undergoing home quarantine during treatment of mild or very mild COVID 19
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Reduction of viral load , indicated by increase in cycle threshold in nasopharyngeal and throat swabs by RT PCR on day 5, 7, 14 as compared to on admission 2.Time taken for clinical cure defined as Normalization of pyrexia and body pain Respiratory rate less than 24 per minute SpO2 rate more than 94 percent Relief from cough Relief from anosmia, for a period of 72 hour 3.Proportion of patients with swabs negative for SARS-nCOV on day 5, 7 Timepoint: Day 5, 7, 14. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of patients who progressed to moderate or severe category of COVID-19 on day 7 and day 14. 2. Number of patients having elevated CRP levels on day 7Timepoint: Day 7, 14 | — |
Countries
India
Contacts
Public ContactDr Rinti Banerjee
Indian Institute of Technology,Bombay.
Outcome results
None listed