Health Condition 1: F321- Major depressive disorder, singleepisode, moderate
Conditions
Interventions
Intervention1: vilazodone 20-60mg: Dose of vilazodone drugs was titrated to a maximum permissible dose 20-60mg per day
Control Intervention1: Escitalopram 10-30mg: Dose of Escitalopram was titrated to
Sponsors
Dr P N Suresh Kumar
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age more than 18 and less than 65 years. 2 No antidepressant and antipsychotic exposure for the past 2 months.
Exclusion criteria
Exclusion criteria: 1 Other co-morbid psychiatric disorders. 2 Pregnancy and lactation. 3 Concurrent major life-threatening illness like malignancy, cardiac failure, renal failure etc. 4 Suicidal patients. 5 Alcohol and substance abuse and smokers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endpoint (4 week) Hamilton Depression rating scale-17 scoresTimepoint: At baseline, and at the two week and four week follow up time points. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes included rater blinded endpoint scores on MADRS and CGI-S as well as proportion reporting treatment emergent side effects (diarrhoea, sexual dysfunction and weight gain) at study endpoint.Timepoint: at baseline, and at the two week and four week follow up time points. | — |
Countries
India
Contacts
Public ContactDr P N Suresh Kumar
IQRAA psychiatric care and rehabilitation centre
Outcome results
None listed