Health Condition 1: P22- Respiratory distress of newborn
Conditions
Interventions
Intervention1: Surfactant with budesonide: surfactant in a dose of 100mg/kg/dose mixed with budesonide in a dose of 0.25mg/kg/dose is administered intratracheally to the patient
Control Intervention1:
Sponsors
Munmun Sahney
Eligibility
Inclusion criteria
Inclusion criteria: Receiving mechanical ventilation via an endotracheal tube, or infants receiving non-invasive respiratory support including continuous positive airway pressure (CPAP), non-invasive intermittent positive pressure ventilation (NIPPV) or nasal high flow (HF), and a clinical decision to treat the infant with exogenous surfactant.
Exclusion criteria
Exclusion criteria: 1. Infant is considered non-viable (less than 23 weeks) or is not going to be admitted to the neonatal intensive care unit (NICU) 2. Known or suspected major congenital anomaly that are likely to affect respiratory status (upper airway obstruction, severe pulmonary hypoplasia following oligohydramnios, congenital lung malformation, and major congenital heart disease)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Total duration of respiratory support and supplemental oxygen therapy (Mechanical ventilator, nasal CPAP, HFNC)Timepoint: At discharge and 28 days of life | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Death prior to hospital discharge, 2. Length of hospital stay, 3. BPD, 4. Other major neonatal morbidities (intraventricular haemorrhage, hyperglycemia, gastrointestinal bleed, periventricular leukomalacia, retinopathy of prematurity, necrotizing enterocolitis, spontaneous intestinal perforation, pneumothorax, PDA treated pharmacologically or with surgery, sepsis) Timepoint: At discharge and 28 days of life | — |
Countries
India
Contacts
Public ContactMunmun Sahney
Dr Mehtas Multispeciality hospital
Outcome results
None listed