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Ivabradine in the treatment of inappropriately increased heart rate after cardiac surgery

"Comparison of efficacy of oral ivabradine versus oral metoprolol against postoperative atrial fibrillation in patients undergoing open heart surgery"

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026457
Enrollment
340
Registered
2020-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I279- Pulmonary heart disease, unspecified

Interventions

None listed

Sponsors

SMS Medical College Attached Hospital Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria a). An informed consent________________________________ b). Elective open heart surgery including coronary artery bypass surgery under cardiopulmonary bypass for left main or triple vessel disease and other elective cardiac surgeries.______________________________________ c). Normal preoperative sinus rhythm____________________________________ d). ____

Exclusion criteria

Exclusion criteria: Exclusion criteria a). Previous history of supraventricular arrhythmia, atrial fibrillation, or atrial flutter; _____________________________________________________ b). __Bradycardia or a heart rate less than 50 beats/min (bpm); ________________________________________________________ c). __A second-degree or third-degree atrioventricular block; ________________________________________________________ d). ___evere chronic obstructive pulmonary disease or pulmonary impairment; e). Known hypersensitivity to β-blockers or ivabradine; f). An ejection fraction less than 30% (limiting eligibility to the beta blocker group). g).Absence to follow up

Design outcomes

Primary

MeasureTime frame
Reduction in occurence of atrial fibrillation after open heart surgeryTimepoint: 60 days

Secondary

MeasureTime frame
Reduction in number of hospital admission dayTimepoint: 60 DAYS

Countries

India

Contacts

Public ContactDr Neha Sharma

MD Pharmacology

drlokendra29@gmail.com9414048334

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026