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A prospective study comparing the clinical efficacy of levosimendan with milrinone in pediatric cardiac surgery

A prospective study comparing the clinical efficacy of levosimendan with milrinone - MILE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026449
Enrollment
100
Registered
2020-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I52- Other heart disorders in diseasesclassified elsewhere

Interventions

Intervention1: Levosimendan: Levosimendan infusion is started post-operatively and continued in the ICU Control Intervention1: Milrinone: Milrinone infusion is started and continued postoperatively

Sponsors

Dr Kaushik J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Includes all children with congenital heart disease below 1 year age

Exclusion criteria

Exclusion criteria: Single ventricle physiology RACHS score 5,6 Preoperative LCOS requiring inotropic support Preoperative renal failure, cardiac arrest Preoperative thrombocytopenia

Design outcomes

Primary

MeasureTime frame
Incidence of low cardiac output syndromeTimepoint: During postoperative period—

Secondary

MeasureTime frame
Inotropic requirements Duration of ventilation Length of ICU stay Length of hospital stay Timepoint: 30 days—

Countries

India

Contacts

Public ContactDr Kaushik Jothinath

G Kuppuswamy Naidu Memorial Hospital

scarfacejoe83@gmail.com7795152360

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026